This comes following Herantis' recent pivot away from direct intracerebral delivery for CDNF and towards alternative administration methods, principally intra-nasal

CDNF is a synthetic neurotrophic factor, or protein that helps nerve cells survive. The factor occurs naturally in blood and cerebrospinal fluid. CDNF protected and regenerated nerve cells in studies involving animal models of Parkinson’s disease. It stopped, and to some extent reversed, the progression of the disease.

CDNF, or Cerebral Dopamine Neurotrophic Factor, is an endoplasmic reticulum located and secreted protein with neuroprotective and neurorestorative properties, patented worldwide by Herantis. Encouraged by strong preclinical proof-of-concept Herantis is launching a first-in-human, randomized Phase 1-2 clinical study with CDNF for the treatment of Parkinson's disease in 1H/2017. Herantis Pharma Oyj (“Herantis” tai “Yhtiö”), innovatiivinen kliinisen vaiheen lääkekehitysyhtiö, joka kehittää uusia sairauden kulkuun vaikuttavia regeneratiivisia hoitoja, tiedotti tänään yhtiön hallituksen päättäneen keskittää Herantiksen resurssit yhtiön CDNF- ja xCDNF-ohjelmiin ja aloittaa lisensointikumppanin etsimisen Lymfactinin kliiniselle kehitysohjelmalle CDNF – a biological protein – is Herantis’ lead program and a clinical stage asset; and xCDNF – a synthetic peptide version of CDNF – is Herantis’ follow-on program. Both CDNF and xCDNF have, via their multimodal mechanism of action, the potential improves neuronal survival and to stop the progression of Parkinson’s and other About CDNF. As opposed to other treatment modalities for Parkinson ’s disease, CDNF represents an opportunity to modify the disease state by alleviating both motor and non-motor symptoms and stopping disease progression; effects that Herantis has demonstrated in non-human primates. About Lymfactin Herantis Pharma Oyj: Herantis Pharma keskittyy CDNF- ja xCDNF-ohjelmiin 2021-03-25 Herantis Pharma Oyj: Herantis Pharma on julkaissut vuoden 2020 vuosikertomuksen 2017-10-02 · Herantis Pharma has started the first clinical trial of cerebral dopamine neurotrophic factor (CDNF) as a potential treatment for Parkinson’s disease.

"CDNF mot Parkinsons sjukdom är för närvarande i en första studie på människa (fas 1/2), men vi har Köp aktien Herantis Pharma Oyj (HRNTS). Hos Nordnet kan Herantis Pharma Oyj: Herantis Pharma keskittyy CDNF- ja xCDNF-ohjelmiin. 2021-03-29 11:00 · Herantis Pharma - Early CDNF topline results in Parkinson's safety and tolerability profile of CDNF in Parkinson's
Herantis announced today the Herantis' regenerative medicine drug candidates, CDNF and Lymfactin®, aim to revolutionize the treatment of Parkinson's disease and other neurodegenerative This comes following Herantis' recent pivot away from direct intracerebral delivery for CDNF and towards alternative administration methods, principally intra-nasal All focus now on CDNF and xCDNF · More data presented for Lymfactin and CNS assets. Herantis presented more data on the completed AdeLE Herantis and Nanoform have penned a letter of intent to collaborate to seek to enhance the nasal delivery to the brain of Herantis' two PD candidates, CDNF and Herantis Pharma meddelar positiv "topline"-analys av säkerhet och tolerans i fas 1/2-studier för bolagets läkemedelskandidat CDNF mot Herantis Pharma Plc (“Herantis”), an innovativeclinical stage CDNF biological therapy that acts on the proteostatic mechanisms of disease for Analyser, rekommendationer & riktkurser för Herantis Pharma aktien. Lymfactin results spurs plans to out-license All focus now on CDNF and xCDNF.

Herantis Pharma meddelar positiv "topline"-analys av säkerhet och tolerans i fas 1/2-studier för bolagets läkemedelskandidat CDNF mot

29 March 2021 at 9:00 PM EET. Herantis Pharma Plc (“Herantis or the Company”), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis’ CDNF and xCDNF assets and to commence seeking 2020-02-25 Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease. Herantis Pharma Plc. Company release, Inside Information . 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc ("Herantis or the Company"), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis' CDNF and xCDNF assets and to commence seeking out Herantis Pharma Plc ("Herantis" or "Company") announced today that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson's disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease.

Herantis Pharma Oyj: Herantis Pharma keskittyy CDNF- ja xCDNF-ohjelmiin 2021-03-25 Herantis Pharma Oyj: Herantis Pharma on julkaissut vuoden 2020 vuosikertomuksen

Data reported for the first six months are preliminary in this first-in-human clinical study for this novel MOA drug class.

We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization. 2021-03-10 Herantis Pharma Oyj: Herantis Pharma to focus on CDNF and xCDNF programs 2021-03-25 07:00 · Cision Herantis Pharma Oyj: Herantis Pharma Published the Annual Report for the Financial Year 2020 Herantis Pharma Plc (“Herantis” or “Company”) announced today an update on the development of its non-invasive next generation CDNF, or xCDNF. The xCDNF development program was initiated in July 2018 to develop cell-protecting molecules that penetrate the blood-brain barrier, building on the Company’s cumulated expertise on CDNF, Herantis’ lead compound in Parkinson disease. 2019-09-26 Herantis Pharma Plc. Company release, Inside Information 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc ("Herantis or the Company"), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis' CDNF and xCDNF assets and to commence seeking out 2017-10-02 Thus, Herantis has decided to evaluate the best path forward with its clinical stage asset CDNF, using alternative administration methods.
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29 March 2021 at 9:00 PM EET. Herantis Pharma Plc (“Herantis or the Company”), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis’ CDNF and xCDNF assets and to commence seeking Herantis Pharma Announces an Oral Presentation and a Poster Presentation related to First-in-Man CDNF Clinical Trial at AD/PD™ Virtual Conference Read more Proposals of the Shareholders’ Nomination Committee to Herantis Pharma Plc’s Annual General Meeting 2021 Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease. Intracerebral delivery abandonedMore patient friendly methods to be exploredA fresh start with an accelerated development trajectoryIntracerebral delivery deeme Herantis Pharma Plc. Company release, Inside Information 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc ("Herantis or the Company"), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis' CDNF and xCDNF assets and to commence seeking out “ CDNF is now one of a few clinical stage assets in development with the potential for disease modification of Parkinson’s Disease. The intranasal administration route of CDNF is an important program for Herantis to maximize the chances of success for CDNF in brain disorders. CDNF bygger i grunden på en upptäckt av bl a Mart Saarma som själv även är delägare i Herantis.

Both CDNF and xCDNF have, via their multimodal mechanism of action, the potential improves neuronal survival and to stop the progression of Parkinson’s and other CDNF - a biological protein - is Herantis' lead program and a clinical stage asset; and xCDNF - a synthetic peptide version of CDNF - is Herantis' follow-on program. Both CDNF and xCDNF have, via their multimodal mechanism of action, the potential improves neuronal survival and to stop the progression of Parkinson's and other neurodegenerative disease and have a significant therapeutic impact on the lives of patients.
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16 Oct 2017 In addition to CDNF, Herantis Pharma is developing the drug candidate Lymfactin® for the treatment of breast cancer associated lymphedema.

Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease. Based on internationally recognized science, Herantis’ drug development pipeline targets breakthroughs in diseases with unmet clinical need. We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization. Herantis Pharma Plc is an innovative drug development company looking to break the boundaries of standard therapeutic approaches.

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2021-03-29 · Herantis Pharma Plc. Company release, Inside Information . 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc ("Herantis or the Company"), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis' CDNF and xCDNF assets and to commence seeking out

Herantis Pharma Oyj ("Herantis" tai "Yhtiö") tiedotti tänään alustavia tuloksia CDNF-lääkeaihion Vaiheen 1-2 kliinisestä tutkimuksesta Parkinsonin tautia sairastavissa potilaissa. CDNF on Herantiksen yksinoikeudella kehittämä, hermosoluja suojaava lääkeaihio, jonka tavoitteena on muuttaa Parkinsonin taudinkulkua, mikä olisi merkittävä läpimurto verrattuna tunnettuihin In order to do this, Herantis has developed xCDNF, a patented, chemically synthesised form of CDNF that uses small but potent biologically active fragments of the parent CDNF molecule, which it says can reach the key areas of the brain in therapeutic concentrations using a simple dosing method such as subcutaneous injection. Herantis Pharma is focused on the development of innovative regenerative medicines targeting unmet needs.

“ CDNF is now one of a few clinical stage assets in development with the potential for disease modification of Parkinson’s Disease. The intranasal administration route of CDNF is an important program for Herantis to maximize the chances of success for CDNF in brain disorders.

2020-02-25 · Source: Herantis It is cold this time of year in Helsinki, but there will be some warm smiles there today. A small biotech firm called Herantis Pharma has announced the topline results of their Phase 1/2 clinical trial exploring the safety and tolerability of a treatment called CDNF.